Amaryl 4 mg is the brand name for glimepiride, an oral medication used to treat type 2 diabetes mellitus. It belongs to a class of drugs called sulfonylureas, which work by stimulating the pancreas to release insulin. The Amaryl 4 mg dosage is one of several strengths available and is typically prescribed when lower doses are not sufficient to control blood sugar levels. Amaryl is not used to treat type 1 diabetes or diabetic ketoacidosis. Amaryl 4 mg is usually taken once daily with breakfast or the first main meal.