Intestine-on-a-chip models integrate microfluidic technology with tissue engineering to replicate the physiological and pathological conditions of the human gut. These models simulate key features such as intestinal epithelial cell interactions, vascular endothelial integration, and host-microbe dynamics. Researchers use intestine-on-a-chip systems to study digestion, barrier integrity, immune regulation, and drug metabolism, providing a more accurate platform for personalized research strategies and therapeutic development.
